
Tirzepatide for Weight Loss – programs start at $125 per week.
Tirzepatide is a newer medication that has gained attention for its remarkable effectiveness in promoting weight loss. It acts as a dual agonist for two key receptors involved in metabolic regulation: GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1). This dual action sets tirzepatide apart from other weight loss medications, as it influences both pathways to enhance insulin sensitivity, control blood sugar, and significantly reduce appetite.
How Tirzepatide Works:
- GIP Receptor Activation: This pathway enhances insulin secretion in a glucose-dependent manner, improves insulin sensitivity, and may have direct effects on fat metabolism.
- GLP-1 Receptor Activation: Like semaglutide, it reduces appetite, slows gastric emptying, and improves insulin response, helping with weight loss.
Weight Loss Effects:
Tirzepatide has shown even more dramatic weight loss results than GLP-1 medications like semaglutide. In clinical studies, people treated with tirzepatide experienced an average weight loss of 16-26% of their body weight, making it one of the most effective pharmacological interventions available for obesity and overweight conditions.
Brands:
- Mounjaro: Initially approved for the treatment of type 2 diabetes, Mounjaro has shown promising off-label results for weight loss.
- Zepbound: Approved specifically for weight management, Zepbound is the brand focused on obesity treatment.
Cost:
Tirzepatide’s price typically starts at around $125 per week, making it more expensive than some alternatives like semaglutide, but its potential for greater weight loss might make it a worthwhile investment for certain individuals.
Mechanisms:
- Appetite Suppression: Like GLP-1 agonists, tirzepatide reduces appetite and increases feelings of fullness.
- Increased Fat Metabolism: The GIP pathway may contribute to a higher rate of fat breakdown.
- Improved Blood Sugar Control: It significantly improves insulin sensitivity, helping people manage their blood sugar levels while losing weight.
Side Effects:
The side effects of Tirzepatide are similar to those of GLP-1 medications and may include:
- Nausea
- Diarrhea
- Vomiting
- Constipation
- Fatigue
These side effects are usually more common when starting the medication and tend to diminish over time.
Benefits Over GLP-1 Medications:
Tirzepatide’s dual action gives it a potential advantage over traditional GLP-1 drugs like Semaglutide, offering enhanced weight loss and improved metabolic outcomes. It might be particularly beneficial for individuals who need more significant weight loss or better glycemic control.
Conclusion:
Tirzepatide is emerging as a powerful option for weight management, especially for individuals who need to lose a substantial amount of weight. With an average loss of 16-26% of body weight, it can provide significant health benefits, but its higher cost (starting at $125 per week) may be a consideration for some.
As always, consulting a healthcare provider is essential to see if tirzepatide is the right choice based on your specific medical history and weight loss goals.
Some of the side effects of GLP-1 medications including nausea, vomiting, diarrhea, pancreatitis, gastroparesis, bowel obstruction, gallstone attacks, and bile duct blockage.
People those who are supper responders to GIP / GLP-1 medications report a 16-28% loss of body weight. The recommended dose for Semaglutide is as follows
Week 1 to week 4 2.5 mg
Week 5 to week 8 5.0 mg
Week 9 to week 12 7.5 mg
Week 13 to week 16 10mg
Once the goal weight is achieved this medication should be tapered off in coordination with the prescriber.
Due to many restrictions for weight loss drugs, we at weightrizi only accept self paying patients. Our price for office visits with Evaluation for Management of Weight Control is $199 and only qualified patients can get prescription for Mounjaro Pens or Zepbound pens.